
TB4 (TB-500)
10mg · 2ml
SKU: tb4-10mg
TB-500 (Thymosin Beta-4) is a peptide derived from the naturally occurring Thymosin Beta-4 protein that plays a key role in cell migration, tissue regeneration, and inflammation reduction. It operates through actin sequestration to facilitate cellular migration to injury sites, promote angiogenesis, and enhance tissue remodeling.
Product Specifications
Strength
10mg
Volume / Qty
2ml
Form
Lyophilized Powder
Suggested Retail Price
$110.00
Dosing Guide
Recommended Dose
250-500 mcg of each peptide
Route
Subcutaneous
Frequency
Daily or divided BID
Clinician Access Required
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TB4 (TB-500) is available exclusively to verified clinicians under IRB-approved research protocol PPRN-001-2025.
IRB-Approved Research Protocol
PPRN-001-2025 ·IRCM-2025-467
Approved December 3, 2025 · Principal Investigator: Dr. M. Scott Mortensen, MD, MPAS, MLT
Save up to 80% with the 5,000 Foundation Bundle
TB4 (TB-500) is included in this clinic-tier package. Bundle includes weight loss (tirz & reta) + longevity/repair (mots-c, ghk-cu, bpc-157, epithalon) with 1 free Tirz 15mg as a bonus.
For Clinicians
Clinical Reference
Pharmacology, safety, monitoring, and dosing reference for TB4 (TB-500). Always individualize based on patient context.
Mechanism of Action
Receptor / Target
Actin-sequestering protein; modulates VEGF, IL-4, and laminin-5 expression
Half-Life
~2 hours (subcutaneous)
Onset of Action
1–3 weeks for tissue remodeling
Metabolism
43-amino-acid peptide; cleared via proteolysis
Cautions & Contraindications
Contraindicated In
- Active malignancy (angiogenic activity)
- Known hypersensitivity to thymosin beta-4
Use Caution With
- Pregnancy and lactation (insufficient data)
- Cycle duration typically 4–6 weeks; reassess before extending
- Use in 1:1 ratio with BPC-157 for combination protocols
Suggested Labs to Monitor
CBC with differential
Baseline / 6 weeksCMP
Baseline / 6 weekshs-CRP
Baseline / 4 weeksInflammation marker for tissue repair tracking.
Lab interpretation guidance comes from peer-reviewed literature. Always individualize based on patient context.
Reconstitution Calculator
Calculate exactly how many units to draw on a U-100 insulin syringe for your target dose. Pre-filled with TB4 (TB-500) defaults — adjust as needed.
Total peptide in the vial (e.g. 10mg)
Volume of BAC water used to reconstitute
Single-injection dose in micrograms
Draw to
Per mL
5000 mcg
Doses per vial
~40
Always double-check reconstitution math. This tool is for reference — clinician supervision required.
Plumb DISCOVER
What TB4 (TB-500) targets
Patient goals, biomarkers, and wearable signals this peptide addresses. Powers the future Plumb AI protocol engine.
Patient Goals
Biomarkers Tracked
Wearable Signals
Essential Protocol Packages
TB4 (TB-500) is part of 2 clinical protocols
Bundle this peptide with synergistic compounds at clinic-tier pricing.

Aesthetic & Tissue Regeneration Comparison Protocol
Compare multi-peptide regenerative formulation (GLOW) vs higher-dose GHK-Cu monotherapy, with optional glutathione support.

Soft-Tissue Repair & Regenerative Support Protocol
Focused tissue repair protocol combining BPC-157 and TB-500 for musculoskeletal and soft-tissue recovery.
Clinical Synergy
Frequently stacked with TB4 (TB-500)
Peptides commonly combined with TB4 (TB-500) for synergistic clinical outcomes.
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BPC-157/TB500 20mg
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