Epithalon
50mg · 5ml
SKU: epithalon-50mg
Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) originally isolated from the pineal gland that activates telomerase to extend chromosome telomere length. It supports DNA repair, cellular regeneration, and circadian rhythm regulation, potentially slowing cellular aging processes.
Product Specifications
Strength
50mg
Volume / Qty
5ml
Form
Lyophilized Powder
Suggested Retail Price
$170.00
Dosing Guide
Recommended Dose
5-10 mg daily
Route
Subcutaneous
Frequency
Daily
Clinician Access Required
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Epithalon is available exclusively to verified clinicians under IRB-approved research protocol PPRN-001-2025.
IRB-Approved Research Protocol
PPRN-001-2025 ·IRCM-2025-467
Approved December 3, 2025 · Principal Investigator: Dr. M. Scott Mortensen, MD, MPAS, MLT
Save up to 80% with the 5,000 Foundation Bundle
Epithalon is included in this clinic-tier package. Bundle includes weight loss (tirz & reta) + longevity/repair (mots-c, ghk-cu, bpc-157, epithalon) with 1 free Tirz 15mg as a bonus.
For Clinicians
Clinical Reference
Pharmacology, safety, monitoring, and dosing reference for Epithalon. Always individualize based on patient context.
Mechanism of Action
Receptor / Target
Tetrapeptide (Ala-Glu-Asp-Gly); upregulates telomerase and pineal melatonin synthesis
Half-Life
~30 minutes (subcutaneous)
Onset of Action
2–4 weeks for circadian/sleep effects; longer for telomere effects
Metabolism
Renal and hepatic proteolysis
Cautions & Contraindications
Contraindicated In
- Active malignancy (theoretical with telomerase activation)
- Pregnancy and lactation
- Hypersensitivity to epithalon
Use Caution With
- Cycle 10–20 days, 1–2 cycles annually
- Avoid concurrent estrogen-positive cancers
- Evening dosing aligns with melatonin synthesis
Suggested Labs to Monitor
CBC, CMP
Baseline / annuallyIGF-1
Baseline / annuallyLongevity peptides interact with the GH/IGF axis.
Cortisol AM and DHEA-S
Baseline / annuallyCircadian and adrenal axis monitoring.
Lab interpretation guidance comes from peer-reviewed literature. Always individualize based on patient context.
Reconstitution Calculator
Calculate exactly how many units to draw on a U-100 insulin syringe for your target dose. Pre-filled with Epithalon defaults — adjust as needed.
Total peptide in the vial (e.g. 10mg)
Volume of BAC water used to reconstitute
Single-injection dose in micrograms
Draw to
Per mL
10000 mcg
Doses per vial
~200
Always double-check reconstitution math. This tool is for reference — clinician supervision required.
Plumb DISCOVER
What Epithalon targets
Patient goals, biomarkers, and wearable signals this peptide addresses. Powers the future Plumb AI protocol engine.
Patient Goals
Biomarkers Tracked
Wearable Signals
Essential Protocol Packages
Epithalon is part of 2 clinical protocols
Bundle this peptide with synergistic compounds at clinic-tier pricing.
Neuroplasticity & Circadian Optimization Protocol
Neuroendocrine support for circadian rhythm, neuroplasticity, and cognitive resilience.
Longevity Protocol
Comprehensive anti-aging and longevity protocol targeting telomeres, senescence, and mitochondrial health.
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